To sum it up "According to [philosopher William] James, we choose our truth by what difference it will make in practice." The reason this caught my eye is I'm a huge fan of denying all types of moral relativism, which is what pragmatism is... moral relativism masquerading as something deeper. As opposed to divine law, pragmatism (and other moral systems) always boil down to something that is mutable. In pragmatism the key words, as far as relativism is concerned, are "we choose". Pragmatism, even though focused on the practical application of moral choices, still hinges ones' choice.
One of the concepts the History of Philosophy podcast mentioned about the innovations brought about by Plato/Socrates was how he made philosophy about finding out how one ought to live. It seems to me that while Socrates was real and in many ways accurately portrayed by Plato, it's really Plato's genius that gave Socrates to the world, and thereby, really it was Plato that changed philosophy for the whole western world. Philosophy has become so generalized it has lost much of its meaning. Don't get me wrong there are all sorts of people seeking practical application in today's world, but if you're following relativistic thinking (any kind) you have to constantly be rethinking your ethics because they change.
That's not to say that divine moralists don't have to consider new issues as they arise; as science changes what we can do (especially medically) we have new things to consider. Notice I didn't say "progress" I've always thought that just because something is new doesn't mean it's better. Don't get me wrong, I don't think we should go back to the middle ages, there are tons of great advances brought about by science; life is much easier now, maybe too easy, we are a very overweight culture.